Cargando…
Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission
The amyloid precursor protein (APP) modulates synaptic activity, resulting from the fine tuning of excitatory and inhibitory neurotransmission. GABAergic inhibitory neurotransmission is affected by modifications in intracellular chloride concentrations regulated by Na(+)-K(+)-2Cl(−) cotransporter 1...
Autores principales: | Doshina, Anna, Gourgue, Florian, Onizuka, Michiho, Opsomer, Remi, Wang, Peng, Ando, Kunie, Tasiaux, Bernadette, Dewachter, Ilse, Kienlen-Campard, Pascal, Brion, Jean-Pierre, Gailly, Philippe, Octave, Jean-Noël, Pierrot, Nathalie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428293/ https://www.ncbi.nlm.nih.gov/pubmed/28337033 http://dx.doi.org/10.1038/s41598-017-00325-2 |
Ejemplares similares
-
Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release
por: Opsomer, Rémi, et al.
Publicado: (2020) -
Epigenetic Induction of EGR-1 Expression by the Amyloid Precursor Protein during Exposure to Novelty
por: Hendrickx, Aurélie, et al.
Publicado: (2013) -
Epigenetic Regulations of Immediate Early Genes Expression Involved in Memory Formation by the Amyloid Precursor Protein of Alzheimer Disease
por: Hendrickx, Aurélie, et al.
Publicado: (2014) -
Sex-regulated gene dosage effect of PPARα on synaptic plasticity
por: Pierrot, Nathalie, et al.
Publicado: (2019) -
Amyloid precursor protein controls cholesterol turnover needed for neuronal activity
por: Pierrot, Nathalie, et al.
Publicado: (2013)