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Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms

Aminoacyl-tRNA synthetases (aaRSs) charge tRNAs with their cognate amino acid, an essential precursor step to loading of charged tRNAs onto the ribosome and addition of the amino acid to the growing polypeptide chain during protein synthesis. Because of this important biological function, aminoacyl-...

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Detalles Bibliográficos
Autores principales: Moen, Spencer O., Edwards, Thomas E., Dranow, David M., Clifton, Matthew C., Sankaran, Banumathi, Van Voorhis, Wesley C., Sharma, Amit, Manoil, Colin, Staker, Bart L., Myler, Peter J., Lorimer, Donald D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428304/
https://www.ncbi.nlm.nih.gov/pubmed/28303005
http://dx.doi.org/10.1038/s41598-017-00367-6