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Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms
Aminoacyl-tRNA synthetases (aaRSs) charge tRNAs with their cognate amino acid, an essential precursor step to loading of charged tRNAs onto the ribosome and addition of the amino acid to the growing polypeptide chain during protein synthesis. Because of this important biological function, aminoacyl-...
Autores principales: | Moen, Spencer O., Edwards, Thomas E., Dranow, David M., Clifton, Matthew C., Sankaran, Banumathi, Van Voorhis, Wesley C., Sharma, Amit, Manoil, Colin, Staker, Bart L., Myler, Peter J., Lorimer, Donald D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428304/ https://www.ncbi.nlm.nih.gov/pubmed/28303005 http://dx.doi.org/10.1038/s41598-017-00367-6 |
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