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Cholesterol attenuates cytoprotective effects of phosphatidylcholine against bile salts

Bile salts have potent detergent properties and damaging effects on cell membranes, leading to liver injury. However, the molecular mechanisms for the protection of hepatocytes against bile salts are not fully understood. In this study, we demonstrated that the cytotoxicity of nine human major bile...

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Detalles Bibliográficos
Autores principales: Ikeda, Yoshito, Morita, Shin-ya, Terada, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428433/
https://www.ncbi.nlm.nih.gov/pubmed/28331225
http://dx.doi.org/10.1038/s41598-017-00476-2