Nod2 and Nod2-regulated microbiota protect BALB/c mice from diet-induced obesity and metabolic dysfunction

Genetics plays a central role in susceptibility to obesity and metabolic diseases. BALB/c mice are known to be resistant to high fat diet (HFD)-induced obesity, however the genetic cause remains unknown. We report that deletion of the innate immunity antibacterial gene Nod2 abolishes this resistance...

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Detalles Bibliográficos
Autores principales: Rodriguez-Nunez, Ivan, Caluag, Tiffany, Kirby, Kori, Rudick, Charles N., Dziarski, Roman, Gupta, Dipika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428441/
https://www.ncbi.nlm.nih.gov/pubmed/28373658
http://dx.doi.org/10.1038/s41598-017-00484-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428441/
https://www.ncbi.nlm.nih.gov/pubmed/28373658
http://dx.doi.org/10.1038/s41598-017-00484-2

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