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Apigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling
The bioflavonoid apigenin has been shown to possess cancer-preventive and anti-cancer activities. In a drug screening, we found that apigenin can inhibit Wnt/β-catenin signaling, a pathway that participates in pivotal biological functions, which dis-regulation results in various human diseases inclu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428476/ https://www.ncbi.nlm.nih.gov/pubmed/28337019 http://dx.doi.org/10.1038/s41598-017-00409-z |