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Apigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling

The bioflavonoid apigenin has been shown to possess cancer-preventive and anti-cancer activities. In a drug screening, we found that apigenin can inhibit Wnt/β-catenin signaling, a pathway that participates in pivotal biological functions, which dis-regulation results in various human diseases inclu...

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Detalles Bibliográficos
Autores principales:	Lin, Chung-Ming, Chen, Hsin-Han, Lin, Chun-An, Wu, Hui-Chung, Sheu, Jim Jinn-Chyuan, Chen, Hui-Jye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428476/ https://www.ncbi.nlm.nih.gov/pubmed/28337019 http://dx.doi.org/10.1038/s41598-017-00409-z

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