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Exploring Approaches for Detecting Protein Functional Similarity within an Orthology-based Framework
Protein functional similarity based on gene ontology (GO) annotations serves as a powerful tool when comparing proteins on a functional level in applications such as protein-protein interaction prediction, gene prioritization, and disease gene discovery. Functional similarity (FS) is usually quantif...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428484/ https://www.ncbi.nlm.nih.gov/pubmed/28336965 http://dx.doi.org/10.1038/s41598-017-00465-5 |