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Inhibition of serum and glucocorticoid regulated kinase-1 as novel therapy for cardiac arrhythmia disorders

Alterations in sodium flux (I(Na)) play an important role in the pathogenesis of cardiac arrhythmias and may also contribute to the development of cardiomyopathies. We have recently demonstrated a critical role for the regulation of the voltage-gated sodium channel Na(V)1.5 in the heart by the serum...

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Detalles Bibliográficos
Autores principales: Bezzerides, Vassilios J., Zhang, Aifeng, Xiao, Ling, Simonson, Bridget, Khedkar, Santosh A., Baba, Shiro, Ottaviano, Filomena, Lynch, Stacey, Hessler, Katherine, Rigby, Alan C., Milan, David, Das, Saumya, Rosenzweig, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428512/
https://www.ncbi.nlm.nih.gov/pubmed/28336914
http://dx.doi.org/10.1038/s41598-017-00413-3