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Seven perspectives on GPCR H/D-exchange proteomics methods

Recent research shows surging interest to visualize human G protein-coupled receptor (GPCR) dynamic structures using the bottom-up H/D-exchange (HDX) proteomics technology. This opinion article clarifies critical technical nuances and logical thinking behind the GPCR HDX proteomics method, to help s...

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Detalles Bibliográficos
Autor principal: Zhang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428523/
https://www.ncbi.nlm.nih.gov/pubmed/28529698
http://dx.doi.org/10.12688/f1000research.10667.1