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Gene length and detection bias in single cell RNA sequencing protocols

Background: Single cell RNA sequencing (scRNA-seq) has rapidly gained popularity for profiling transcriptomes of hundreds to thousands of single cells. This technology has led to the discovery of novel cell types and revealed insights into the development of complex tissues. However, many technical...

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Detalles Bibliográficos
Autores principales: Phipson, Belinda, Zappia, Luke, Oshlack, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428526/
https://www.ncbi.nlm.nih.gov/pubmed/28529717
http://dx.doi.org/10.12688/f1000research.11290.1