The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity

Chemotherapy-induced peripheral neuropathic pain (CIPN) is a common and severe debilitating side effect of many widely used cytostatics. However, there is no approved pharmacological treatment for CIPN available. Among other substances, oxaliplatin causes CIPN in up to 80% of treated patients. Here,...

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Detalles Bibliográficos
Autores principales: Hohmann, Stephan W., Angioni, Carlo, Tunaru, Sorin, Lee, Seungkyu, Woolf, Clifford J., Offermanns, Stefan, Geisslinger, Gerd, Scholich, Klaus, Sisignano, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428564/
https://www.ncbi.nlm.nih.gov/pubmed/28348394
http://dx.doi.org/10.1038/s41598-017-00591-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428564/
https://www.ncbi.nlm.nih.gov/pubmed/28348394
http://dx.doi.org/10.1038/s41598-017-00591-0

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