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The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity
Chemotherapy-induced peripheral neuropathic pain (CIPN) is a common and severe debilitating side effect of many widely used cytostatics. However, there is no approved pharmacological treatment for CIPN available. Among other substances, oxaliplatin causes CIPN in up to 80% of treated patients. Here,...
Autores principales: | Hohmann, Stephan W., Angioni, Carlo, Tunaru, Sorin, Lee, Seungkyu, Woolf, Clifford J., Offermanns, Stefan, Geisslinger, Gerd, Scholich, Klaus, Sisignano, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428564/ https://www.ncbi.nlm.nih.gov/pubmed/28348394 http://dx.doi.org/10.1038/s41598-017-00591-0 |
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