The TLR2 Binding Neisserial Porin PorB Enhances Antigen Presenting Cell Trafficking and Cross-presentation

TOLL-like receptor (TLR) ligands activate both innate and adaptive immune cells, while modulating the cellular immune response. The outer membrane protein (OMP) from Neisseria meninigitidis, PorB, is a naturally occurring TLR2 ligand and functions as an adjuvant. Here, we demonstrate that PorB incre...

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Detalles Bibliográficos
Autores principales: Reiser, Michael L., Mosaheb, Munir M., Lisk, Christina, Platt, Andrew, Wetzler, Lee M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428659/
https://www.ncbi.nlm.nih.gov/pubmed/28389664
http://dx.doi.org/10.1038/s41598-017-00555-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428659/
https://www.ncbi.nlm.nih.gov/pubmed/28389664
http://dx.doi.org/10.1038/s41598-017-00555-4

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