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The TLR2 Binding Neisserial Porin PorB Enhances Antigen Presenting Cell Trafficking and Cross-presentation
TOLL-like receptor (TLR) ligands activate both innate and adaptive immune cells, while modulating the cellular immune response. The outer membrane protein (OMP) from Neisseria meninigitidis, PorB, is a naturally occurring TLR2 ligand and functions as an adjuvant. Here, we demonstrate that PorB incre...
Autores principales: | Reiser, Michael L., Mosaheb, Munir M., Lisk, Christina, Platt, Andrew, Wetzler, Lee M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428659/ https://www.ncbi.nlm.nih.gov/pubmed/28389664 http://dx.doi.org/10.1038/s41598-017-00555-4 |
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