Identification of small molecule inhibitors of Interleukin-18

Interleukin-18 (IL-18) is a pleiotropic pro-inflammatory cytokine belonging to the IL-1 superfamily. IL-18 plays an important role in host innate and adaptive immune defense but its aberrant activities are also associated with inflammatory diseases such as rheumatoid arthritis and Crohn's disea...

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Detalles Bibliográficos
Autores principales: Krumm, Brian, Meng, Xiangzhi, Xiang, Yan, Deng, Junpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428663/
https://www.ncbi.nlm.nih.gov/pubmed/28352119
http://dx.doi.org/10.1038/s41598-017-00532-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428663/
https://www.ncbi.nlm.nih.gov/pubmed/28352119
http://dx.doi.org/10.1038/s41598-017-00532-x

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