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Activity and connectivity changes of central projection areas revealed by functional magnetic resonance imaging in Na(V)1.8-deficient mice upon cold signaling

The voltage-gated sodium channel subtype Na(V)1.8 is expressed in the peripheral nervous system in primary afferent nociceptive C-fibers and is essential for noxious cold signaling. We utilized functional magnetic resonance imaging on Na(V)1.8-deficient (Na(V)1.8(−/−)) compared with wildtype (WT) mi...

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Detalles Bibliográficos
Autores principales: Heindl-Erdmann, C., Zimmermann, K., Reeh, P., Brune, K., Hess, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428718/
https://www.ncbi.nlm.nih.gov/pubmed/28373680
http://dx.doi.org/10.1038/s41598-017-00524-x