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Activity and connectivity changes of central projection areas revealed by functional magnetic resonance imaging in Na(V)1.8-deficient mice upon cold signaling
The voltage-gated sodium channel subtype Na(V)1.8 is expressed in the peripheral nervous system in primary afferent nociceptive C-fibers and is essential for noxious cold signaling. We utilized functional magnetic resonance imaging on Na(V)1.8-deficient (Na(V)1.8(−/−)) compared with wildtype (WT) mi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428718/ https://www.ncbi.nlm.nih.gov/pubmed/28373680 http://dx.doi.org/10.1038/s41598-017-00524-x |