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Circulating Tumor DNA Mutation Profiling by Targeted Next Generation Sequencing Provides Guidance for Personalized Treatments in Multiple Cancer Types

Cancer is a disease of complex genetic alterations, and comprehensive genetic diagnosis is beneficial to match each patient to appropriate therapy. However, acquisition of representative tumor samples is invasive and sometimes impossible. Circulating tumor DNA (ctDNA) is a promising tool to use as a...

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Detalles Bibliográficos
Autores principales: Shu, Yongqian, Wu, Xue, Tong, Xiaoling, Wang, Xiaonan, Chang, Zhili, Mao, Yu, Chen, Xiaofeng, Sun, Jing, Wang, Zhenxin, Hong, Zhuan, Zhu, Liangjun, Zhu, Chunrong, Chen, Jun, Liang, Ying, Shao, Huawu, Shao, Yang W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428730/
https://www.ncbi.nlm.nih.gov/pubmed/28373672
http://dx.doi.org/10.1038/s41598-017-00520-1