Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication

A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication. A number of positive allosteric modulators (PAMs)...

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Detalles Bibliográficos
Autores principales: Tian, Jide, Dang, Hoa, Middleton, Blake, Kaufman, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428733/
https://www.ncbi.nlm.nih.gov/pubmed/28336918
http://dx.doi.org/10.1038/s41598-017-00515-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428733/
https://www.ncbi.nlm.nih.gov/pubmed/28336918
http://dx.doi.org/10.1038/s41598-017-00515-y

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