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IL-1β induced HIF-1α inhibits the differentiation of human FOXP3(+) T cells

Differentiation of regulatory Treg (Treg) in the periphery is critical to control inflammatory processes. Although polarization of inducible Treg (iTreg) often occurs in an inflammatory environment, the effects exerted by inflammation on human iTreg differentiation have not been extensively studied....

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Detalles Bibliográficos
Autores principales: Feldhoff, Lea M., Rueda, Cesar M., Moreno-Fernandez, Maria E., Sauer, Johanna, Jackson, Courtney M., Chougnet, Claire A., Rupp, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428734/
https://www.ncbi.nlm.nih.gov/pubmed/28352109
http://dx.doi.org/10.1038/s41598-017-00508-x