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IL-1β induced HIF-1α inhibits the differentiation of human FOXP3(+) T cells
Differentiation of regulatory Treg (Treg) in the periphery is critical to control inflammatory processes. Although polarization of inducible Treg (iTreg) often occurs in an inflammatory environment, the effects exerted by inflammation on human iTreg differentiation have not been extensively studied....
Autores principales: | Feldhoff, Lea M., Rueda, Cesar M., Moreno-Fernandez, Maria E., Sauer, Johanna, Jackson, Courtney M., Chougnet, Claire A., Rupp, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428734/ https://www.ncbi.nlm.nih.gov/pubmed/28352109 http://dx.doi.org/10.1038/s41598-017-00508-x |
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