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HMGB1 induces lung fibroblast to myofibroblast differentiation through NF-κB-mediated TGF-β1 release

The proinflammatory factor high-mobility group box protein 1 (HMGB1) has been implicated in the pathogenesis of lung fibrosis; however, the role of HMGB1 in lung fibrosis remains unclear. It has previously been reported that nuclear factor (NF)-κB and transforming growth factor (TGF)-β1 may be invol...

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Detalles Bibliográficos
Autores principales: Wang, Qiong, Wang, Jun, Wang, Junfang, Hong, Shanchao, Han, Feifei, Chen, Jingyu, Chen, Guoqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428737/
https://www.ncbi.nlm.nih.gov/pubmed/28339089
http://dx.doi.org/10.3892/mmr.2017.6364