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Probabilistic modeling of bifurcations in single-cell gene expression data using a Bayesian mixture of factor analyzers

Modeling bifurcations in single-cell transcriptomics data has become an increasingly popular field of research. Several methods have been proposed to infer bifurcation structure from such data, but all rely on heuristic non-probabilistic inference. Here we propose the first generative, fully probabi...

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Detalles Bibliográficos
Autores principales: Campbell, Kieran R, Yau, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428745/
https://www.ncbi.nlm.nih.gov/pubmed/28503665
http://dx.doi.org/10.12688/wellcomeopenres.11087.1