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Blocking the Nav1.8 channel in the left stellate ganglion suppresses ventricular arrhythmia induced by acute ischemia in a canine model

Left stellate ganglion (LSG) hyperactivity promotes ischemia induced ventricular arrhythmia (VA). Blocking the Nav1.8 channel decreases neuron activity. Therefore, the present study aimed to investigate whether blocking the Nav1.8 channel with its specific blocker A-803467 in the LSG reduces sympath...

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Detalles Bibliográficos
Autores principales: Yu, Lilei, Wang, Menglong, Hu, Dan, Huang, Bing, Zhou, Liping, Zhou, Xiaoya, Wang, Zhuo, Wang, Songyun, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428783/
https://www.ncbi.nlm.nih.gov/pubmed/28373696
http://dx.doi.org/10.1038/s41598-017-00642-6