Cargando…

A Convenient Cas9-based Conditional Knockout Strategy for Simultaneously Targeting Multiple Genes in Mouse

The most powerful way to probe protein function is to characterize the consequence of its deletion. Compared to conventional gene knockout (KO), conditional knockout (cKO) provides an advanced gene targeting strategy with which gene deletion can be performed in a spatially and temporally restricted...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jiang, Du, Yinan, He, Xueyan, Huang, Xingxu, Shi, Yun S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428785/
https://www.ncbi.nlm.nih.gov/pubmed/28364122
http://dx.doi.org/10.1038/s41598-017-00654-2