Enhanced oral bioavailability of valsartan using a polymer-based supersaturable self-microemulsifying drug delivery system

A novel, supersaturable self-microemulsifying drug delivery system (S-SMEDDS) was successfully formulated to enhance the dissolution and oral absorption of valsartan (VST), a poorly water-soluble drug, while reducing the total quantity for administration. Poloxamer 407 is a selectable, supersaturati...

Descripción completa

Detalles Bibliográficos
Autores principales: Yeom, Dong Woo, Chae, Bo Ram, Son, Ho Yong, Kim, Jin Han, Chae, Jun Soo, Song, Seh Hyon, Oh, Dongho, Choi, Young Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428796/
https://www.ncbi.nlm.nih.gov/pubmed/28507434
http://dx.doi.org/10.2147/IJN.S136599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428796/
https://www.ncbi.nlm.nih.gov/pubmed/28507434
http://dx.doi.org/10.2147/IJN.S136599

Ejemplares similares