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Enhanced oral bioavailability of valsartan using a polymer-based supersaturable self-microemulsifying drug delivery system

A novel, supersaturable self-microemulsifying drug delivery system (S-SMEDDS) was successfully formulated to enhance the dissolution and oral absorption of valsartan (VST), a poorly water-soluble drug, while reducing the total quantity for administration. Poloxamer 407 is a selectable, supersaturati...

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Detalles Bibliográficos
Autores principales:	Yeom, Dong Woo, Chae, Bo Ram, Son, Ho Yong, Kim, Jin Han, Chae, Jun Soo, Song, Seh Hyon, Oh, Dongho, Choi, Young Wook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428796/ https://www.ncbi.nlm.nih.gov/pubmed/28507434 http://dx.doi.org/10.2147/IJN.S136599

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