Single cell imaging and quantification of TDP-43 and α-synuclein intercellular propagation

The intercellular spreading of protein assemblies is a major factor in the progression of neurodegenerative disorders. The quantitative study and visualization of cell-to-cell propagation using tagged-proteins is challenging due to the steric effect of relatively large fluorescence tags and the risk...

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Detalles Bibliográficos
Autores principales: Peled, Sivan, Sade, Dorin, Bram, Yaron, Porat, Ziv, Kreiser, Topaz, Mimouni, Michael, Lichtenstein, Alexandra, Segal, Daniel, Gazit, Ehud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428807/
https://www.ncbi.nlm.nih.gov/pubmed/28373710
http://dx.doi.org/10.1038/s41598-017-00657-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428807/
https://www.ncbi.nlm.nih.gov/pubmed/28373710
http://dx.doi.org/10.1038/s41598-017-00657-z

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