Cargando…
Single cell imaging and quantification of TDP-43 and α-synuclein intercellular propagation
The intercellular spreading of protein assemblies is a major factor in the progression of neurodegenerative disorders. The quantitative study and visualization of cell-to-cell propagation using tagged-proteins is challenging due to the steric effect of relatively large fluorescence tags and the risk...
Autores principales: | Peled, Sivan, Sade, Dorin, Bram, Yaron, Porat, Ziv, Kreiser, Topaz, Mimouni, Michael, Lichtenstein, Alexandra, Segal, Daniel, Gazit, Ehud |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428807/ https://www.ncbi.nlm.nih.gov/pubmed/28373710 http://dx.doi.org/10.1038/s41598-017-00657-z |
Ejemplares similares
-
Active Immunization Against hIAPP Oligomers Ameliorates the Diabetes- Associated Phenotype in a Transgenic Mice Model
por: Bram, Yaron, et al.
Publicado: (2017) -
TDP-43 is intercellularly transmitted across axon terminals
por: Feiler, Marisa S., et al.
Publicado: (2015) -
Mechanisms of TDP-43 Proteinopathy Onset and Propagation
por: Chen, Han-Jou, et al.
Publicado: (2021) -
Propagation of TDP-43 proteinopathy in neurodegenerative disorders
por: Keszycki, Rachel, et al.
Publicado: (2021) -
Antibodies towards Tyrosine Amyloid-Like Fibrils Allow Toxicity Modulation and Cellular Imaging of the Assemblies
por: Zaguri, Dor, et al.
Publicado: (2018)