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TRPV1 temperature activation is specifically sensitive to strong decreases in amino acid hydrophobicity
Several transient receptor potential (TRP) ion channels can be directly activated by hot or cold temperature with high sensitivity. However, the structures and molecular mechanism giving rise to their high temperature sensitivity are not fully understood. One hypothesized mechanism assumes that temp...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428820/ https://www.ncbi.nlm.nih.gov/pubmed/28373693 http://dx.doi.org/10.1038/s41598-017-00636-4 |