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PAR1-mediated c-Jun activation promotes heat stress-induced early stage apoptosis of human umbilical vein endothelial cells

Our previous study indicated that when human umbilical vein endothelial cells (HUVECs), which are involved in endothelial barrier function, are heat stressed, levels of protease-activated receptor 1 (PAR1) are increased significantly. In the present study, it was demonstrated that PAR1 serves a vita...

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Detalles Bibliográficos
Autores principales: Zhang, Shuang, Liu, Yanan, Wang, Zhenglian, Liu, Jingxian, Gu, Zhengtao, Xu, Qiulin, Su, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428901/
https://www.ncbi.nlm.nih.gov/pubmed/28447716
http://dx.doi.org/10.3892/mmr.2017.6303