Cargando…

KDM1A/LSD1 regulates the differentiation and maintenance of spermatogonia in mice

The proper regulation of spermatogenesis is crucial to ensure the continued production of sperm and fertility. Here, we investigated the function of the H3K4me2 demethylase KDM1A/LSD1 during spermatogenesis in developing and adult mice. Conditional deletion of Kdm1a in the testis just prior to birth...

Descripción completa

Detalles Bibliográficos
Autores principales: Myrick, Dexter A., Christopher, Michael A., Scott, Alyssa M., Simon, Ashley K., Donlin-Asp, Paul G., Kelly, William G., Katz, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428937/
https://www.ncbi.nlm.nih.gov/pubmed/28498828
http://dx.doi.org/10.1371/journal.pone.0177473