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Proteomic profiling of mdx-4cv serum reveals highly elevated levels of the inflammation-induced plasma marker haptoglobin in muscular dystrophy

X-linked muscular dystrophy is caused by primary abnormalities in the Dmd gene and is characterized by the almost complete loss of the membrane cytoskeletal protein dystrophin, which triggers sarcolemmal instability, abnormal calcium homeostasis, increased proteolysis and impaired excitation-contrac...

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Detalles Bibliográficos
Autores principales: Murphy, Sandra, Dowling, Paul, Zweyer, Margit, Henry, Michael, Meleady, Paula, Mundegar, Rustam R., Swandulla, Dieter, Ohlendieck, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428965/
https://www.ncbi.nlm.nih.gov/pubmed/28440464
http://dx.doi.org/10.3892/ijmm.2017.2952