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Measurement of tissue azithromycin levels in self-collected vaginal swabs post treatment using liquid chromatography and tandem mass spectrometry (LC-MS/MS)

BACKGROUND: Azithromycin is recommended for the treatment of uncomplicated urogenital chlamydia infection although the standard 1gram dose sometimes fails to eradicate the infection (treatment failure). One hypothesis proposed for treatment failure has been insufficient levels of the antibiotic at t...

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Detalles Bibliográficos
Autores principales: Vodstrcil, Lenka A., Rupasinghe, Thusitha W. T., Kong, Fabian Y. S., Tull, Dedreia, Worthington, Karen, Chen, Marcus Y., Huston, Wilhelmina M., Timms, Peter, McConville, Malcolm J., Fairley, Christopher K., Bradshaw, Catriona S., Tabrizi, Sepehr N., Hocking, Jane S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428968/
https://www.ncbi.nlm.nih.gov/pubmed/28498845
http://dx.doi.org/10.1371/journal.pone.0177615