Adaptive tuning of mutation rates allows fast response to lethal stress in Escherichia coli

While specific mutations allow organisms to adapt to stressful environments, most changes in an organism's DNA negatively impact fitness. The mutation rate is therefore strictly regulated and often considered a slowly-evolving parameter. In contrast, we demonstrate an unexpected flexibility in...

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Detalles Bibliográficos
Autores principales: Swings, Toon, Van den Bergh, Bram, Wuyts, Sander, Oeyen, Eline, Voordeckers, Karin, Verstrepen, Kevin J, Fauvart, Maarten, Verstraeten, Natalie, Michiels, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Genomics and Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429094/
https://www.ncbi.nlm.nih.gov/pubmed/28460660
http://dx.doi.org/10.7554/eLife.22939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429094/
https://www.ncbi.nlm.nih.gov/pubmed/28460660
http://dx.doi.org/10.7554/eLife.22939

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