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Role of NLRP3 Inflammasomes in Atherosclerosis

Inflammation with macrophage infiltration is a key feature of atherosclerosis. Although the mechanisms had been unclear, emerging evidence unveiled that NLRP3 inflammasomes, which regulate caspase-1 activation and subsequent processing of pro-IL-1β, trigger vascular wall inflammatory responses and l...

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Detalles Bibliográficos
Autores principales: Karasawa, Tadayoshi, Takahashi, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429158/
https://www.ncbi.nlm.nih.gov/pubmed/28260724
http://dx.doi.org/10.5551/jat.RV17001