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Sequestration of polyunsaturated fatty acids in membrane phospholipids of Caenorhabditis elegans dauer larva attenuates eicosanoid biosynthesis for prolonged survival

Mechanistic basis governing the extreme longevity and developmental quiescence of dauer juvenile, a “non-ageing” developmental variant of Caenorhabditis elegans, has remained largely obscure. Using a lipidomic approach comprising multiple reaction monitoring transitions specific to distinct fatty ac...

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Detalles Bibliográficos
Autores principales: Lam, Sin Man, Wang, Zehua, Li, Jie, Huang, Xun, Shui, Guanghou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429230/
https://www.ncbi.nlm.nih.gov/pubmed/28499251
http://dx.doi.org/10.1016/j.redox.2017.05.002