Crosstalk between HDAC6 and Nox2-based NADPH oxidase mediates HIV-1 Tat-induced pro-inflammatory responses in astrocytes

Histone deacetylase 6 (HDAC6) likely is important in inflammatory diseases. However, how HDAC6 exerts its effect on inflammatory processes remains unclear. HIV-1 transactivator of transcription (Tat) activates NADPH oxidase resulting in generation of reactive oxygen species (ROS), leading to extensi...

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Detalles Bibliográficos
Autores principales: Youn, Gi Soo, Cho, Hyundong, Kim, Donggyu, Choi, Soo Young, Park, Jinseu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429231/
https://www.ncbi.nlm.nih.gov/pubmed/28499252
http://dx.doi.org/10.1016/j.redox.2017.05.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429231/
https://www.ncbi.nlm.nih.gov/pubmed/28499252
http://dx.doi.org/10.1016/j.redox.2017.05.001

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