The microRNA-7-mediated reduction in EPAC-1 contributes to vascular endothelial permeability and eNOS uncoupling in murine experimental retinopathy

AIMS: To investigate the consequences of oxidative stress and hypoxia on EPAC-1 expression during retinopathy. METHODS: Oxygen-induced retinopathy was induced in mice and EPAC-1 expression investigated by immunofluorescence. In silico analyses were used to identify a link between EPAC-1 expression a...

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Detalles Bibliográficos
Autores principales: Garcia-Morales, Veronica, Friedrich, Julian, Jorna, Lysanne M., Campos-Toimil, Manuel, Hammes, Hans-Peter, Schmidt, Martina, Krenning, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429352/
https://www.ncbi.nlm.nih.gov/pubmed/28353063
http://dx.doi.org/10.1007/s00592-017-0985-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429352/
https://www.ncbi.nlm.nih.gov/pubmed/28353063
http://dx.doi.org/10.1007/s00592-017-0985-y

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