DTNI: a novel toxicogenomics data analysis tool for identifying the molecular mechanisms underlying the adverse effects of toxic compounds

Unravelling gene regulatory networks (GRNs) influenced by chemicals is a major challenge in systems toxicology. Because toxicant-induced GRNs evolve over time and dose, the analysis of global gene expression data measured at multiple time points and doses will provide insight in the adverse effects...

Descripción completa

Detalles Bibliográficos
Autores principales: Hendrickx, Diana M., Souza, Terezinha, Jennen, Danyel G. J., Kleinjans, Jos C. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Toxicogenomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429357/
https://www.ncbi.nlm.nih.gov/pubmed/28032149
http://dx.doi.org/10.1007/s00204-016-1922-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429357/
https://www.ncbi.nlm.nih.gov/pubmed/28032149
http://dx.doi.org/10.1007/s00204-016-1922-5

Ejemplares similares