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Preconditioning of bone marrow-derived mesenchymal stromal cells by tetramethylpyrazine enhances cell migration and improves functional recovery after focal cerebral ischemia in rats

BACKGROUND: Transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) is one of the new therapeutic strategies for treating ischemic stroke. However, the relatively poor migratory capacity of BMSCs toward infarcted regions limited the therapeutic potential of this approach. Pharmacologic...

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Detalles Bibliográficos
Autores principales: Li, Lin, Chu, Lisheng, Fang, Yan, Yang, Yan, Qu, Tiebing, Zhang, Jianping, Yin, Yuanjun, Gu, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429508/
https://www.ncbi.nlm.nih.gov/pubmed/28499457
http://dx.doi.org/10.1186/s13287-017-0565-7