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Effects of annulus defects and implantation of poly(lactic-co-glycolic acid) (PLGA)/fibrin gel scaffolds on nerves ingrowth in a rabbit model of annular injury disc degeneration

BACKGROUND: Growth of nerve fibers has been shown to occur in a rabbit model of intravertebral disc degeneration (IVD) induced by needle puncture. As nerve growth may underlie the process of chronic pain in humans affected by disc degeneration, we sought to investigate the factors underlying nerve i...

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Detalles Bibliográficos
Autores principales: Xin, Long, Xu, Weixing, Yu, Leijun, Fan, Shunwu, Wang, Wei, Yu, Fang, Wang, Zhenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429511/
https://www.ncbi.nlm.nih.gov/pubmed/28499451
http://dx.doi.org/10.1186/s13018-017-0572-5