Surface displaying of swine IgG1 Fc enhances baculovirus-vectored vaccine efficacy by facilitating viral complement escape and mammalian cell transduction

Baculovirus-mediated gene transfer has been developed as a vaccine design strategy against a number of diseases without apparent viral replication. However, it has been hampered by complement-dependent inactivation, thus hindering the in vivo application of baculovirus. A variety of approaches have...

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Detalles Bibliográficos
Autores principales: Liu, Zehui, Liu, Yangkun, Zhang, Yuanyuan, Yang, Yajuan, Ren, Jingjing, Zhang, Xiaoying, Du, Enqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429525/
https://www.ncbi.nlm.nih.gov/pubmed/28499403
http://dx.doi.org/10.1186/s13567-017-0434-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429525/
https://www.ncbi.nlm.nih.gov/pubmed/28499403
http://dx.doi.org/10.1186/s13567-017-0434-5

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