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Genome-wide DNA methylation analysis reveals hypomethylation in the low-CpG promoter regions in lymphoblastoid cell lines

BACKGROUND: Epidemiological studies of DNA methylation profiles may uncover the molecular mechanisms through which genetic and environmental factors contribute to the risk of multifactorial diseases. There are two types of commonly used DNA bioresources, peripheral blood cells (PBCs) and EBV-transfo...

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Detalles Bibliográficos
Autores principales: Taniguchi, Itsuki, Iwaya, Chihiro, Ohnaka, Keizo, Shibata, Hiroki, Yamamoto, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429538/
https://www.ncbi.nlm.nih.gov/pubmed/28499412
http://dx.doi.org/10.1186/s40246-017-0106-6