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Transcription and chromatin determinants of de novo DNA methylation timing in oocytes

BACKGROUND: Gametogenesis in mammals entails profound re-patterning of the epigenome. In the female germline, DNA methylation is acquired late in oogenesis from an essentially unmethylated baseline and is established largely as a consequence of transcription events. Molecular and functional studies...

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Detalles Bibliográficos
Autores principales: Gahurova, Lenka, Tomizawa, Shin-ichi, Smallwood, Sébastien A., Stewart-Morgan, Kathleen R., Saadeh, Heba, Kim, Jeesun, Andrews, Simon R., Chen, Taiping, Kelsey, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429541/
https://www.ncbi.nlm.nih.gov/pubmed/28507606
http://dx.doi.org/10.1186/s13072-017-0133-5