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Transcription and chromatin determinants of de novo DNA methylation timing in oocytes
BACKGROUND: Gametogenesis in mammals entails profound re-patterning of the epigenome. In the female germline, DNA methylation is acquired late in oogenesis from an essentially unmethylated baseline and is established largely as a consequence of transcription events. Molecular and functional studies...
Autores principales: | Gahurova, Lenka, Tomizawa, Shin-ichi, Smallwood, Sébastien A., Stewart-Morgan, Kathleen R., Saadeh, Heba, Kim, Jeesun, Andrews, Simon R., Chen, Taiping, Kelsey, Gavin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429541/ https://www.ncbi.nlm.nih.gov/pubmed/28507606 http://dx.doi.org/10.1186/s13072-017-0133-5 |
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