Characterization of a splice-site mutation in the tumor suppressor gene FLCN associated with renal cancer

BACKGROUND: Renal cell carcinoma is among the most prevalent malignancies. It is generally sporadic. However, genetic studies of rare familial forms have led to the identification of mutations in causative genes such as VHL and FLCN. Mutations in the FLCN gene are the cause of Birt-Hogg-Dubé syndrom...

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Detalles Bibliográficos
Autores principales: Bartram, Malte P., Mishra, Tripti, Reintjes, Nadine, Fabretti, Francesca, Gharbi, Hakam, Adam, Alexander C., Göbel, Heike, Franke, Mareike, Schermer, Bernhard, Haneder, Stefan, Benzing, Thomas, Beck, Bodo B., Müller, Roman-Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429543/
https://www.ncbi.nlm.nih.gov/pubmed/28499369
http://dx.doi.org/10.1186/s12881-017-0416-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429543/
https://www.ncbi.nlm.nih.gov/pubmed/28499369
http://dx.doi.org/10.1186/s12881-017-0416-5

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