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Genome-wide DNA methylation analysis in lung fibroblasts co-cultured with silica-exposed alveolar macrophages

BACKGROUND: Exposure to crystalline silica is considered to increase the risk of lung fibrosis. The primary effector cell, the myofibroblast, plays an important role in the deposition of extracellular matrix (ECM). DNA methylation change is considered to have a potential effect on myofibroblast diff...

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Detalles Bibliográficos
Autores principales: Li, Juan, Yao, Wu, Zhang, Lin, Bao, Lei, Chen, Huiting, Wang, Di, Yue, Zhongzheng, Li, Yiping, Zhang, Miao, Hao, Changfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429546/
https://www.ncbi.nlm.nih.gov/pubmed/28499430
http://dx.doi.org/10.1186/s12931-017-0576-z