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Genome-wide DNA methylation analysis in lung fibroblasts co-cultured with silica-exposed alveolar macrophages
BACKGROUND: Exposure to crystalline silica is considered to increase the risk of lung fibrosis. The primary effector cell, the myofibroblast, plays an important role in the deposition of extracellular matrix (ECM). DNA methylation change is considered to have a potential effect on myofibroblast diff...
Autores principales: | Li, Juan, Yao, Wu, Zhang, Lin, Bao, Lei, Chen, Huiting, Wang, Di, Yue, Zhongzheng, Li, Yiping, Zhang, Miao, Hao, Changfu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429546/ https://www.ncbi.nlm.nih.gov/pubmed/28499430 http://dx.doi.org/10.1186/s12931-017-0576-z |
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