The role of TGF-β and its crosstalk with RAC1/RAC1b signaling in breast and pancreas carcinoma

This article focusses on the role of TGF-β and its signaling crosstalk with the RHO family GTPases RAC1 and RAC1b in the progression of breast and pancreatic carcinoma. The aggressive nature of these tumor types is mainly due to metastatic dissemination. Metastasis is facilitated by desmoplasia, a p...

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Detalles Bibliográficos
Autores principales: Melzer, Catharina, Hass, Ralf, von der Ohe, Juliane, Lehnert, Hendrik, Ungefroren, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429551/
https://www.ncbi.nlm.nih.gov/pubmed/28499439
http://dx.doi.org/10.1186/s12964-017-0175-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429551/
https://www.ncbi.nlm.nih.gov/pubmed/28499439
http://dx.doi.org/10.1186/s12964-017-0175-0

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